VetriScience - Supplements for Dogs - Canine Vetri SAMe 225mg - 30TABSVetri SAMe 225 supports liver health and function in dogs of all sizes. The combination of SAMe (S Adenosylmethionine) and powerful antioxidant glutathione acts as the first line of defense for your dogs liver. SAMe is involved in many of the livers biochemical reactions, including detoxification and antioxidant defense. SAMe supports production of glutathione, which is a critical antioxidant for detoxification of drugs and toxins in the liver.